[16] Southampton 1-1 Brighton [9] 2021-12-04 15:00
Stadium: St. Mary's Stadium Round: 15
Referee: Anthony Taylor Home Manager: Ralph Hasenhuttl Away Manager: Graham Potter
Head to Head
| Anglia - Premier League | 2021/03/14 12:00 | Southampton v Brighton | L | 1-2 |
| Anglia - Premier League | 2020/12/07 20:00 | Brighton v Southampton | W | 1-2 |
| Anglia - Premier League | 2020/07/16 19:15 | Southampton v Brighton | D | 1-1 |
| Anglia - Premier League | 2019/08/24 14:00 | Brighton v Southampton | W | 0-2 |
| Anglia - Premier League | 2019/03/30 15:00 | Brighton v Southampton | W | 0-1 |
| Anglia - Premier League | 2018/09/17 19:00 | Southampton v Brighton | D | 2-2 |
| Anglia - Cupa EFL | 2018/08/28 18:45 | Brighton v Southampton | W | 0-1 |
| Anglia - Premier League | 2018/01/31 19:45 | Southampton v Brighton | D | 1-1 |
Home History
| Anglia - Premier League | 2021/12/01 19:30 | Southampton v Leicester | D | 2-2 |
| Anglia - Premier League | 2021/11/27 15:00 | Liverpool v Southampton | L | 4-0 |
| Anglia - Premier League | 2021/11/20 15:00 | Norwich v Southampton | L | 2-1 |
| Anglia - Premier League | 2021/11/05 20:00 | Southampton v Aston Villa | W | 1-0 |
| Anglia - Premier League | 2021/10/30 14:00 | Watford v Southampton | W | 0-1 |
| Anglia - Cupa EFL | 2021/10/26 18:45 | Chelsea v Southampton | L | 5-4 |
| Anglia - Premier League | 2021/10/23 14:00 | Southampton v Burnley | D | 2-2 |
| Anglia - Premier League | 2021/10/16 14:00 | Southampton v Leeds | W | 1-0 |
Away History
| Anglia - Premier League | 2021/12/01 19:30 | West Ham v Brighton | D | 1-1 |
| Anglia - Premier League | 2021/11/27 17:30 | Brighton v Leeds | D | 0-0 |
| Anglia - Premier League | 2021/11/20 15:00 | Aston Villa v Brighton | L | 2-0 |
| Anglia - Premier League | 2021/11/06 17:30 | Brighton v Newcastle | D | 1-1 |
| Anglia - Premier League | 2021/10/30 14:00 | Liverpool v Brighton | D | 2-2 |
| Anglia - Cupa EFL | 2021/10/27 18:45 | Leicester v Brighton | L | 6-4 |
| Anglia - Premier League | 2021/10/23 16:30 | Brighton v Man City | L | 1-4 |
| Anglia - Premier League | 2021/10/16 14:00 | Norwich v Brighton | D | 0-0 |