Stadium: Estadio Round: 14 Ground: Hardcourt outdoor
| Challenger - Ambato | 2021/09/19 17:00 | Matias Zukas v Matias Franco Descotte | 6-4,7-6 |
| Challenger - Tallahassee | 2022/04/18 17:00 | Daniel Dutra Da Silva v Matias Franco Descotte | 6-1,6-4 |
| Challenger - Tallahassee | 2022/04/17 17:45 | Matias Franco Descotte v Sho Shimabukuro | 6-2,6-4 |
| ITF - M15 Sunrise | 2022/04/14 14:00 | Matias Franco Descotte v Bruno Kuzuhara | 6-3,3-6,4-6 |
| ITF - M15 Sunrise | 2022/04/13 14:00 | Matias Franco Descotte v Khololwam Montsi | 0-6,6-0,6-4 |
| Challenger - Salinas | 2022/04/05 19:20 | Andrea Collarini v Matias Franco Descotte | 7-5,6-3 |
| Challenger - Salinas | 2022/04/04 17:55 | Matias Franco Descotte v Saketh Myneni | 7-6,7-6 |
| Challenger - Salinas | 2022/04/03 18:00 | Matias Franco Descotte v Jorge Panta | 6-1,3-6,6-4 |
| Challenger - Pereira | 2022/03/28 16:35 | Conner Huertas Del Pino v Matias Franco Descotte | 6-4,5-7,6-4 |
| Challenger - Aguascalientes | 2022/04/21 16:00 | Juan Pablo Ficovich v Matias Zukas | 6-2,6-3 |
| Challenger - Aguascalientes | 2022/04/19 22:50 | Rodrigo Pacheco Mendez v Matias Zukas | 4-6,4-6 |
| Challenger - Aguascalientes | 2022/04/18 18:15 | Roberto Quiroz v Matias Zukas | 1-6,2-6 |
| Challenger - Aguascalientes | 2022/04/17 18:30 | Matias Zukas v Gabriel Decamps | 6-1,6-3 |
| Challenger - San Luis Potosi | 2022/04/12 19:35 | Jay Clarke v Matias Zukas | 6-3,6-4 |
| Challenger - San Luis Potosi | 2022/04/11 18:00 | Matias Zukas v Mohamed Safwat | 3-6,6-3,6-4 |
| Challenger - San Luis Potosi | 2022/04/10 16:00 | Skander Mansouri v Matias Zukas | 2-6,6-7 |
| Challenger - Pereira | 2022/03/27 15:00 | Rio Noguchi v Matias Zukas | 6-1,6-2 |