[4] Club America 3-2 Puebla [5] 2022-05-14 23:00
Stadium: Estadio Azteca Round: 3
Referee: Julio Gerardo Garcia Armenta Home Manager: Fernando Ortiz Away Manager: Nicolas Larcamon
Head to Head
| Mexic - Liga MX | 2022/05/12 02:05 | Puebla v Club America | D | 1-1 |
| Mexic - Liga MX | 2022/01/08 03:00 | Puebla v Club America | D | 1-1 |
| Mexic - Liga MX | 2021/08/08 00:00 | Club America v Puebla | W | 2-0 |
| Mexic - Liga MX | 2021/02/07 01:00 | Club America v Puebla | W | 1-0 |
| Mexic - Liga MX | 2020/09/09 02:00 | Puebla v Club America | W | 2-3 |
| Mexic - Liga MX | 2020/02/05 02:30 | Puebla v Club America | W | 0-1 |
| Mexic - Liga MX | 2019/10/27 00:00 | Club America v Puebla | W | 2-0 |
| Mexic - Liga MX | 2019/03/10 01:00 | Club America v Puebla | W | 1-0 |
Home History
| Mexic - Liga MX | 2022/05/12 02:05 | Puebla v Club America | D | 1-1 |
| Mexic - Liga MX | 2022/05/01 02:00 | Club America v Cruz Azul | D | 0-0 |
| Mexic - Liga MX | 2022/04/24 00:00 | Tigres UANL v Club America | W | 0-2 |
| Mexic - Liga MX | 2022/04/21 02:00 | Club America v Leon | W | 2-0 |
| Mexic - Liga MX | 2022/04/16 02:06 | Tijuana v Club America | W | 1-3 |
| Mexic - Liga MX | 2022/04/10 02:00 | Club America v Juarez FC | W | 3-0 |
| Mexic - Liga MX | 2022/04/03 01:00 | Necaxa v Club America | W | 0-1 |
| America - Amicale | 2022/03/24 01:02 | Club America v Tigres UANL | L | 1-2 |
Away History
| Mexic - Liga MX | 2022/05/12 02:05 | Puebla v Club America | D | 1-1 |
| Mexic - Liga MX | 2022/05/08 22:00 | Puebla v Mazatlan FC | W | 5-3 |
| Mexic - Liga MX | 2022/04/30 02:05 | Mazatlan FC v Puebla | L | 2-1 |
| Mexic - Liga MX | 2022/04/23 00:00 | Puebla v Necaxa | L | 0-1 |
| Mexic - Liga MX | 2022/04/20 00:00 | Pachuca v Puebla | L | 1-0 |
| Mexic - Liga MX | 2022/04/16 22:00 | Leon v Puebla | W | 0-1 |
| Mexic - Liga MX | 2022/04/09 00:00 | Puebla v Unam Pumas | D | 2-2 |
| Mexic - Liga MX | 2022/04/03 17:00 | Toluca v Puebla | L | 2-1 |