Stadium: Rice-Totten Stadium Round: 1
Home Manager: Vincent Dancy Away Manager:
| NCAAF | 2022/09/10 20:00 | Mississippi Valley State v Austin Peay | L | 0-41 |
| NCAAF | 2022/09/02 00:00 | Mississippi Valley State v Tarleton State | L | 13-29 |
| NCAAF | 2021/11/27 20:00 | Mississippi Valley State v Prairie View | W | 24-19 |
| NCAAF | 2021/11/13 19:00 | Alabama State v Mississippi Valley State | W | 31-44 |
| NCAAF | 2021/11/06 18:00 | Mississippi Valley State v Alabama | L | 14-42 |
| NCAAF | 2021/10/30 20:00 | Jackson State v Mississippi Valley State | L | 28-19 |
| NCAAF | 2021/10/23 20:00 | Florida A&M v Mississippi Valley State | L | 31-28 |
| NCAAF | 2021/10/16 20:00 | Alcorn State v Mississippi Valley State | L | 24-12 |
| NCAAF | 2022/09/10 18:00 | McKendree v Delta State | W | 34-58 |
| NCAAF | 2022/09/03 17:00 | Kentucky Thorobreds v Delta State | W | 10-33 |
| NCAAF | 2021/11/13 18:00 | West Georgia Wolves v Delta State | L | 44-7 |
| NCAAF | 2021/11/06 19:00 | Delta State v Mississippi College Choctaws | W | 24-21 |
| NCAAF | 2021/10/30 19:00 | Delta State v Shorter Hawks | W | 14-13 |
| NCAAF | 2021/10/23 21:00 | West Alabama Tigers v Delta State | W | 30-35 |
| NCAAF | 2021/10/16 19:00 | Delta State v North Greenville Crusaders | L | 34-42 |
| NCAAF | 2021/10/09 23:00 | Valdosta State v Delta State | L | 55-0 |