| Paraguay - Liga - Feminin | 2022/05/03 19:00 | Guairena FC - Feminin v Club Guarani - Feminin | W | 1-3 |
| Paraguay - Liga - Feminin | 2022/08/08 14:00 | Cerro Porteno - Feminin v Club Guarani - Feminin | L | 3-1 |
| Paraguay - Liga - Feminin | 2022/08/01 14:00 | Sportivo Ameliano - Feminin v Club Guarani - Feminin | W | 1-5 |
| Paraguay - Liga - Feminin | 2022/07/15 14:00 | Club Guarani - Feminin v Tacuary - Feminin | W | 7-0 |
| Paraguay - Liga - Feminin | 2022/07/11 14:00 | Club Guarani - Feminin v Club Olimpia - Feminin | L | 0-2 |
| Paraguay - Liga - Feminin | 2022/07/04 14:00 | Resistencia FC - Feminin v Club Guarani - Feminin | W | 2-3 |
| Paraguay - Liga - Feminin | 2022/06/24 14:00 | Sol de America - Feminin v Club Guarani - Feminin | D | 1-1 |
| Paraguay - Liga - Feminin | 2022/06/17 14:00 | Club Guarani - Feminin v General Caballero JLM - Feminin | W | 3-0 |
| Paraguay - Liga - Feminin | 2022/06/10 13:30 | Club Guarani - Feminin v 12 De Octubre Itaugua - Feminin | W | 8-1 |
| Paraguay - Liga - Feminin | 2022/08/07 19:00 | Guairena FC - Feminin v Resistencia FC - Feminin | W | 3-2 |
| Paraguay - Liga - Feminin | 2022/06/27 14:00 | 12 De Octubre Itaugua - Feminin v Guairena FC - Feminin | W | 0-3 |
| Paraguay - Liga - Feminin | 2022/06/18 19:00 | Tacuary - Feminin v Guairena FC - Feminin | D | 1-1 |
| Paraguay - Liga - Feminin | 2022/05/30 14:00 | CS Limpeno Women v Guairena FC - Feminin | L | 6-0 |
| Paraguay - Liga - Feminin | 2022/05/09 14:00 | Nacional-Humaita - Feminin v Guairena FC - Feminin | D | 3-3 |
| Paraguay - Liga - Feminin | 2022/05/03 19:00 | Guairena FC - Feminin v Club Guarani - Feminin | L | 1-3 |
| Paraguay - Liga - Feminin | 2022/04/30 19:00 | Sportivo Ameliano - Feminin v Guairena FC - Feminin | W | 0-3 |
| Paraguay - Liga - Feminin | 2022/03/06 12:00 | Resistencia FC - Feminin v Guairena FC - Feminin | D | 1-1 |