| Uruguay - Liga de Rezerve | 2022/05/10 18:00 | Defensor Sporting - Rezerve v Cerrito - Rezerve | L | 3-1 |
| Uruguay - Liga de Rezerve | 2022/11/21 17:00 | Cerrito - Rezerve v Albion FC - Rezerve | L | 0-4 |
| Uruguay - Liga de Rezerve | 2022/11/14 19:00 | Torque - Rezerve v Cerrito - Rezerve | D | 1-1 |
| Uruguay - Liga de Rezerve | 2022/11/04 18:00 | Cerrito - Rezerve v Penarol - Rezerve | L | 1-5 |
| Uruguay - Liga de Rezerve | 2022/10/24 18:00 | Cerrito - Rezerve v Atletico Fenix - Rezerve | D | 1-1 |
| Uruguay - Liga de Rezerve | 2022/09/27 18:00 | Cerrito - Rezerve v Cerro Largo - Rezerve | D | 1-1 |
| Uruguay - Liga de Rezerve | 2022/09/06 18:00 | Rentistas - Rezerve v Cerrito - Rezerve | W | 1-2 |
| Uruguay - Liga de Rezerve | 2022/08/30 13:00 | Cerrito - Rezerve v Atletico River Plate Reserves | W | 2-1 |
| Uruguay - Liga de Rezerve | 2022/08/23 18:00 | Deportivo Maldonado - Rezerve v Cerrito - Rezerve | L | 3-0 |
| Uruguay - Liga de Rezerve | 2022/11/21 19:00 | Nacional de Montevideo - Rezerve v Defensor Sporting - Rezerve | L | 3-1 |
| Uruguay - Liga de Rezerve | 2022/11/14 12:30 | Defensor Sporting - Rezerve v Albion FC - Rezerve | W | 5-1 |
| Uruguay - Liga de Rezerve | 2022/11/04 13:00 | Atletico Fenix - Rezerve v Defensor Sporting - Rezerve | L | 5-0 |
| Uruguay - Liga de Rezerve | 2022/10/25 18:00 | Defensor Sporting - Rezerve v Cerro Largo - Rezerve | W | 4-0 |
| Uruguay - Liga de Rezerve | 2022/10/11 13:00 | Atletico River Plate Reserves v Defensor Sporting - Rezerve | D | 0-0 |
| Uruguay - Liga de Rezerve | 2022/09/27 13:00 | Defensor Sporting - Rezerve v Boston River - Rezerve | L | 2-3 |
| Uruguay - Liga de Rezerve | 2022/09/12 18:00 | Defensor Sporting - Rezerve v Penarol - Rezerve | W | 2-1 |
| Uruguay - Liga de Rezerve | 2022/09/06 14:11 | Plaza Colonia - Rezerve v Defensor Sporting - Rezerve | D | 2-2 |