[4] Duke 45-21 Miami Florida [10] 2022-10-22 16:30
Stadium: Hard Rock Stadium Round: 1
Home Manager: Mario Cristobal Away Manager: Mike Elko
Head to Head
| NCAAF | 2021/11/27 17:30 | Miami Florida v Duke | L | 47-10 |
| NCAAF | 2020/12/06 01:00 | Miami Florida v Duke | L | 48-0 |
| NCAAF | 2019/11/30 20:30 | Miami Florida v Duke | W | 17-27 |
| NCAAF | 2018/11/03 23:00 | Duke v Miami Florida | W | 20-12 |
| NCAAF | 2017/09/29 23:00 | Miami Florida v Duke | L | 31-6 |
| NCAAF | 2016/11/26 20:30 | Duke v Miami Florida | L | 21-40 |
| NCAAF | 2015/10/31 23:00 | Duke v Miami Florida | L | 27-30 |
| NCAAF | 2014/09/27 23:30 | Miami Florida v Duke | L | 22-10 |
| NCAAF | 2012/11/24 12:00 | Duke v Miami Florida | L | 45-52 |
| NCAAF | 2011/11/05 12:00 | Miami Florida v Duke | L | 49-14 |
| NCAAF | 2010/10/16 12:00 | Duke v Miami Florida | L | 13-28 |
| NCAAF | 2009/11/21 12:00 | Miami Florida v Duke | L | 34-16 |
| NCAAF | 2008/10/18 12:00 | Duke v Miami Florida | L | 31-49 |
| NCAAF | 2007/09/29 12:00 | Miami Florida v Duke | L | 24-14 |
| NCAAF | 2006/10/21 12:00 | Duke v Miami Florida | L | 15-20 |
| NCAAF | 2005/10/08 12:00 | Miami Florida v Duke | L | 52-7 |