| NIT - Feminin | 03/21 23:00 | 122 | Coll Of Charleston - Feminin v USC Upstate - Feminin | L | 78-60 | |
| WNCAAB | 03/10 01:00 | 2 | [230] Radford - Feminin v USC Upstate - Feminin [185] | L | 61-45 | |
| WNCAAB | 03/07 23:00 | 3 | USC Upstate - Feminin v Longwood - Feminin | W | 60-37 | |
| WNCAAB | 02/28 23:30 | - | Presbyterian - Feminin v USC Upstate - Feminin | L | 47-43 | |
| WNCAAB | 02/24 21:00 | - | USC Upstate - Feminin v Winthrop - Feminin | L | 61-67 | |
| WNCAAB | 02/21 23:00 | - | Charleston Southern - Feminin v USC Upstate - Feminin | L | 66-59 | |
| WNCAAB | 02/17 19:00 | - | USC Upstate - Feminin v Gardner Webb - Feminin | W | 73-56 | |
| WNCAAB | 02/15 00:00 | - | USC Upstate - Feminin v High Point - Feminin | L | 50-53 | |
| WNCAAB | 02/10 18:00 | - | [150] USC Upstate - Feminin v UNC Asheville - Feminin [250] | W | 71-65 | |
| WNCAAB | 02/08 00:00 | - | USC Upstate - Feminin v Longwood - Feminin | W | 49-45 | |
| WNCAAB | 02/03 19:00 | - | Radford - Feminin v USC Upstate - Feminin | L | 67-61 | |
| WNCAAB | 02/01 00:00 | - | USC Upstate - Feminin v Presbyterian - Feminin | W | 62-58 | |
| WNCAAB | 01/27 18:00 | - | Gardner Webb - Feminin v USC Upstate - Feminin | W | 59-78 | |
| WNCAAB | 01/25 00:00 | - | High Point - Feminin v USC Upstate - Feminin | W | 49-59 | |
| WNCAAB | 01/20 21:00 | - | USC Upstate - Feminin v Radford - Feminin | W | 65-60 | |
| WNCAAB | 01/18 00:00 | - | Longwood - Feminin v USC Upstate - Feminin | L | 66-58 | |
| WNCAAB | 01/13 21:00 | - | USC Upstate - Feminin v Charleston Southern - Feminin | W | 59-58 | |
| WNCAAB | 01/06 19:00 | - | Winthrop - Feminin v USC Upstate - Feminin | W | 51-52 | |
| WNCAAB | 01/04 00:00 | - | USC Upstate - Feminin v UNC Asheville - Feminin | W | 71-44 | |
| WNCAAB | 12/20 19:00 | - | [242] USC Upstate - Feminin v Georgia Tech - Feminin [81] | L | 50-81 | |
| WNCAAB | 12/18 16:00 | - | [77] UNC Greensboro - Feminin v USC Upstate - Feminin [219] | L | 56-53 | |
| WNCAAB | 12/09 21:30 | - | [128] Furman - Feminin v USC Upstate - Feminin [246] | W | 58-61 | |
| WNCAAB | 12/05 16:30 | - | [281] USC Upstate - Feminin v Western Carolina - Feminin [305] | W | 73-64 | |
| WNCAAB | 11/30 22:30 | - | [255] USC Upstate - Feminin v Samford - Feminin [143] | L | 52-57 | |
| WNCAAB | 11/25 19:00 | - | [320] North Florida - Feminin v USC Upstate - Feminin [302] | W | 60-73 | |
| WNCAAB | 11/24 19:00 | - | [152] Detroit Mercy - Feminin v USC Upstate - Feminin [288] | L | 71-64 | |
| WNCAAB | 11/21 00:00 | - | [347] South Carolina State - Feminin v USC Upstate - Feminin [318] | W | 53-58 | |
| WNCAAB | 11/17 17:00 | - | USC Upstate - Feminin v Queens - Feminin | L | 51-61 | |
| WNCAAB | 11/15 00:00 | - | USC Upstate - Feminin v AZS CMUJ Krakow - Feminin | W | 72-44 | |
| WNCAAB | 11/11 23:00 | - | [350] USC Upstate - Feminin v Kentucky - Feminin [141] | L | 54-82 |